Scientists discover a yeast protein capable of binding bacterial LPS

June 21, 2023 3:24 pm

The hair-like or wormlike structures from the image above are actually LPS.

They are from S. typhimurium and detected using Transmission Electron Microscopy imaging . Scientists have surprisingly found a ubiquitous protein from yeast (GCN4-pII) which binds bacteria lipopolysaccharides (LPS) with picomolar affinity.

This protein can detect LPS at concentrations as low as 0.062 ng/mL, compared to the Limulus amoebocyte lysate (LAL) assay with a sensitivity as low as 0.125 ng/mL.

GCN4-pII dissolves LPS aggregates in solution and can be used for LPS removal.

At LPS-BioSciences, we use alternative specific biomarkers that target the lipid A moiety of LPS to detect trace amounts of LPS.

Learn more about our expertise by following the link below:

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