SEITE, Sophie, BRETON, Aude, NOVIKOV, Alexey, et al. all bacteria lipopolysaccharides are not endotoxins: Structure to activity relationships: vitreoscilla filiformis example. Journal of the American Academy of Dermatology, 2017, vol. 76, no 6, p. AB36.
Introduction: Endotoxins are the main components of the outer membrane of Gram-negative bacteria. Each bacterium possesses a specific lipopolysaccharides (LPS) structure. Chemically, endotoxins are LPS, but not all LPS are endotoxins. They are composed of two moieties: the polysaccharidic (PS) and the lipid A. The PS moiety is made of the so-called O-antigens linked to core oligosaccharides. They carry the antigenic properties of the molecule and can be used in vaccines as well as in bacterial detection tests. As an example, we studied Vitreoscilla filiformis, a Gram-negative bacterium isolated from spa waters and chosen for its beneficial effects on atopic dermatitis lesions.
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LPS-BIOSCIENCES will be sponsoring the Endotoxin Shock Society Congress 2017 in Paris at the Institut PASTEUR.
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LPS-BIOSCIENCES will be attending the 17th Congress of European Shock Society in Paris, September 13-15, 2017.
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