More than a century ago, Elie Metchnikoff established the bases of cellular innate immunity when he discovered the mechanism of phagocytosis.

However, during most of the XXth century, adaptive immunity (also known as specific immunity) focused most of the interest of the researchers, until Emile Janeway and Polly Matzinger revisited the definition of immunology. What was called “non-specific immunity” was renamed “innate immunity”, and the understanding of the sensing of the exogenous or endogenous dangers signals, and their identification revolutionized our understanding of the early mechanism aimed to defend the integrity of the host against any type of attacks including pathogens.

Nowadays, how bacteria, viruses, parasites and fungi are sensed by the infected host, have been mostly deciphered. Similarly, the mechanisms of the host involved to defend its integrity against infectious process have been decoded. This MOOC describes the players and the whole orchestra involved in innate immunity against pathogens.

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 On December 15th, LPS-BIOSCIENCES attended to this conference day on nosocomial infections. Vaccines, antibacterial molecules, many solutions were presented to fight the dramatic issue of resistant pathogens.





LPS-BIOSCIENCES was selected as recipient by the CNRS for the call for projects against terrorism. This call was organized by Alain Fuchs, president of the National research organisation to promote projects that could help understanding, preventing and struggling against terrorists attacks after the Paris attacks in november.

One year later, LPS-BIOSCIENCES has produced two biological markers of bacteria involved in Bioterrorism to help research in developing new, efficient and rapid diagnostic tests. 

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Martine CAROFF presented our project of producing Antigens from bacteria involved in Bioterrorism to help research develop news diagnostic tools.

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Le domaine des attaques biologiques et chimiques est également au programme de ce vaste programme, afin d'"envisager le pire pour pouvoir l'éviter". La biologiste Martine Caroff établit des biomarqueurs de bactéries classées dans le cadre du bioterrorisme pour permettre une détection rapide en cas d'attaque. "Nous ne sommes pas des spécialistes de la +biodéfense+ mais nous sommes spécialistes de certaines bactéries", dit la chercheuse, souhaitant "apporter sa pierre à l'édifice".



The 10th edition of Lyonbiopole Partnering Days will be held on tuesday, October, 11th in Grenoble. Innovative partnership is placed innovation at the heart of this annual event, with the following program: 20 roundtable brainstorming, flash presentations of technologies and projects, networking moments. Over 300 participants, large companies, SMEs, clinicians and academics will be able to share their expertise, initiate unifying projects to address major health challenges and build the future of medicine.

LPS-BIOSCIENCES has been selected to participate and present its technological innovations during the flash presentations.  Feel free to come and meet us there, if you wish to discuss on endotoxins issues.