Dosage & Removal


Quant-LPS is a range of services designed for industrial companies willing to quantify endotoxins or detergents like triton.

Remov-LPS is a new range of services designed for industrial companies willing to remove endotoxins from therapeutic products.

We provide the following custom services and adapt our methods to your needs:

 

ENDOTOX: Expertise and advice for Endotoxins removal from therapeutic production

  • Guidance for industrial process improvement.
  • Easy and quick : 2 days advisory mission from our endotoxins experts.
  • Adapted to your need: First contact with conference call, review of your data, Complete report with advice and practical solutions, ending conference call to review the report.
  • Benefit: A complete review of your process and the possible solutions available to remove endotoxins.

 

QUANT-LPS: Endotoxins quantification with LC-MS2 or LAL

  • Adapted to your need : Quantification of LPS using different methods (LAL, LC-MS2, GC-MS) depending on matrix and the risk of interference. We can also quantify other chemicals like detergents (Triton)
  • LAL alternative: LC-MS2 quantification method was developed specifically for samples that are difficult to dose using LAL tests.
  • Possible identification: We can also identify the type of endotoxins causing the contamination.
  • Benefit: No interferences. Possible endotoxin quantification in complex samples (Protein, polysaccharides, blood, serum)

 

REMOV-LPS: Endotoxins removal from therapeutic productions

  • LPS removal from therapeutic molecules batch productions:
    • Exo-polysaccharides for vaccine industry
    • Hyaluronic acid for cosmetic industry
  • Specific and adaptive depyrogenation development process and method
  • Benefit: Available industrial process improvement and tech transfer

 

Contact us for a customized price quote.

Dr. Jérôme Thévenon, Head of Microbiology R&D at
CEVA Phylaxia

"An important point, is the ability of LPS-BioSciences to integrate from the start of each project, the industrial and regulatory constraints we are facing, and to provide us results resolving them. "